Most feet blisters are caused by friction and do not require medical attention. New skin will form underneath the affected area and the fluid built up in the blister is absorbed back into the tissue. You can soften and relieve ordinary blisters with Vitamin E ointment or an aloe-based cream.
You should never puncture a blister unless it is large, painful, or there is reason to believe that it’s prone to further irritation. If you do have to pop a blister, use a sterilized needle or razor blade. First make sure to intensively wash the area, then make a small hole and gently squeeze out the fluid (which should be clear). To help protect against infection, apply a dab of hydrogen peroxide. Do not remove the skin over a broken blister! The new skin underneath needs it to act as a protective cover. Simply cover the area with a bandage and mild compression.
Medical attention is required if the fluid is white or yellow as opposed to clear. This is a sign of infection.
Gradually breaking in new shoes and applying petroleum jelly or an adhesive bandage on areas that are being rubbed will help to prevent blisters from forming. Wearing socks with heels and socks made with acrylic and other synthetic-fibers are better choices. Washing and drying your feet daily will help to prevent bacterial infections such as Athlete’s Foot.