Blood clots in the legs of airline travelers were first reported in the 1950s and were termed “traveler’s thrombosis”. The condition is now known as “venous thromboembolism” (VTE) and is not specific to travel. However, long-haul travel is
a significant risk factor for VTE, and the association has been extensively studied in recent years.
An international consensus statement categorizes VTE into three risk groups: low, moderate, and high. High risk includes people with a history of blood clots; malignancy; pregnancy; obesity; and coagulation disorders. The risk of long-haul airline travel ranges from 0-2%
in a low risk person and rises to 5% in a high risk person. Although there is a risk of VTE from all long distance travel including long
rides in cars, buses, and trains, air travel has a much higher risk, up to 26% higher, for unknown reasons.

